Liverpool-born George Stubbs is best known today for his closely-observed, sympathetic paintings of horses and conversation pieces. Humphry knew many of the leading artists of his day. He was friends with George Romney, accompanying him to Italy in 1773. He remained in Italy studying painting until 1777. He put together 'A Memoir of George Stubbs', recording Stubbs's conversations. This was not published until 1870 but is the only contemporary biography of Stubbs. Humphry also corresponded with William Blake and taught John Opie. He is believed to be the artist of what is thought by some to be a portrait of the young Jane Austen, the so-called 'Rice Portrait'.